磁共振成像动脉瘤壁环形强化有助于识别多

磁共振成像动脉瘤壁环形强化有助于识别多发性脑动脉瘤患者的破裂部位

CircumferentialWallEnhancementonMagneticResonanceImagingisUsefultoIdentifyRuptureSiteinPatientswithMultipleCerebralAneurysms

背景：颅内多发性动脉瘤患者破裂部位的识别主要基于动脉瘤的大小、位置和形状。最新研究显示，磁共振（MR）血管壁成像呈现动脉瘤壁环形增强（CEAW）提示为破裂动脉瘤。

BACKGROUND:Identificationofrupturesitesinpatientswithmultipleintracranialaneurysmsislargelybasedonaneurysmsize,location,andshape.Findingcircumferentialenhancementalongtheaneurysmwall(CEAW)onmagneticresonance(MR)vesselwallimagingwasrecentlyshowntobeindicativeofrupturedaneurysm.

目的：探讨较高程度的CEAW能否识别多发性动脉瘤患者的破裂部位。

OBJECTIVE:ToinvestigatethehypothesisthatahigherdegreeofCEAWwouldidentifythesiteofruptureinpatientswithmultipleaneurysms.

方法：作者连续选取发生动脉瘤性蛛网膜下腔出血的多发性动脉瘤患者（26例患者，共计62枚动脉瘤），应用MR血管壁成像前瞻性地进行CEAW定量分析。在注射对比剂前后分别获取三维T1加权快速自旋回波序列，并且计算动脉瘤壁强化指数（WEI）。比较破裂与未破裂动脉瘤的特征（大小、位置、不规则形状、纵横比［瘤颈至瘤顶的长度/瘤颈宽度］和WEI），通过单因素条件性logistic回归分析计算动脉瘤破裂的比值比及95%置信区间，并且经动脉瘤大小校正后再次进行分析。

METHODS:WeprospectivelyperformedquantitativeanalysisofCEAWinconsecutivepatientswithbothaneurysmalsubarachnoidhemorrhageandmultipleaneurysms(26patientswithatotalof62aneurysms),usingMRvesselwallimaging.Three-dimensionalT1-weightedfastspin-echosequenceswereobtainedbeforeandafterinjectionofcontrastmedia,andthewallenhancementindex(WEI)wascalculated.Aneurysmcharacteristics(size,location,irregularshape,aspectratio[neck-to-domelength/neckwidth],andWEI)were







































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